#mrna

Eli Lilly moved into selective degradation of pathogenic autoantibodies with a deal worth up to $2.875B. Elsewhere, open-weight AI models grew markedly in scale, ChatGPT advertising reached a $1B annualized run rate, and data from hundreds of thousands of businesses showed AI use climbing without an apparent employment shock so far.

A CVE was issued for an SQLite vulnerability that doesn't exist, exposing how LLM hallucinations are entering the security infrastructure. Alibaba's Qwen3.8 raised the bar for open-weight coding models, while Dwarkesh Patel argued H100 compute could become 15x more expensive once AI reaches human-engineer capability. BioNTech named a new CEO after a six-month vacancy, and the FTC sued Hims & Hers over patient data privacy violations.

OpenAI quietly launched GPT-5.6 in three tiers (Sol, Terra, Luna) restricted to trusted partners, while Semgrep reported that GLM 5.2 outperforms Claude on its internal cybersecurity benchmarks. Portugal's National Health Service contracted Sword Health to deliver AI-assisted physical therapy nationwide, the first country-scale deployment of its kind. Edison Scientific and Population Health Partners announced a deal to use AI agents for end-to-end drug discovery. Patrick Boyle assessed Brexit's 10-year economic toll, and Noah Smith examined whether AI will push companies toward more or less outsourcing.

Anthropic accused Alibaba of illicitly extracting Claude's model capabilities, drawing 829 Hacker News comments and raising fresh questions about AI IP enforcement. OpenAI unveiled Jalapeño, its first custom inference chip built with Broadcom, a move that reshapes its dependency on Nvidia. GLM-5.2 crossed a threshold Nathan Lambert called the step change for open agents. Google introduced computer use in Gemini 3.5 Flash, and U.S. health spending rose 7.3% in 2025, driven by GLP-1 drug adoption and higher care utilization. A bipartisan bill would expand methadone access by letting physicians prescribe it outside specialty clinics.